Manuel Pellegrini says there are fitness doubts over Felipe Anderson and Sebastien Haller ahead of their weekend clash with Brighton.
The Hammers were no match for Premier League champions Manchester City last weekend, with City running out 5-0 winners at London Stadium, with a tough test against a Brighton, who won 3-0 away from home at Watford on the opening day, to come this Saturday.
The Hammers' task could be made all the more difficult should midfielder Anderson and club-record signing Haller fail to be passed fit, but Pellegrini believes he has the squad to get their season up and running.
"Mark Noble is recovering from his calf injury," Pellegrini said. "I think that next week he will work with the team.
"We also have small problems with Felipe Anderson and Sebastien Haller. They are recovering from the kicks that they had in the last game. We'll see tomorrow about Anderson and Haller, we have some doubts.
"We are not thinking about our targets or achievements in May. One defeat does not change our minds.
"We have a good squad and we must try to play better in the other games. We have just started the season."
Pellegrini also gave an update on Jack Wilshere's fitness, after the midfielder was substituted against City having suffered a dead leg.
"Jack is working without any problems in our squad," Pellegrini added. "He's working with our team. We don't have any problem about that. He's okay."