The north London rivals shared a six-goal thriller in the league earlier this month, and Al Hain-Cole expects another entertaining game in the EFL Cup
Tottenham will be out for revenge when they take on neighbours Arsenal at the Emirates Stadium in Wednesday's EFL Cup clash.
Spurs fell to a 4-2 defeat here at the beginning of this month, but have bounced back with three league wins and an impressive Champions League draw in Barcelona that saw them through to the knockout stages.
In confident spirits, they are available at 9/5 (2.80) to avenge that defeat by securing a first win at this ground since 2010.
Meanwhile, Unai Emery's men suffered their first defeat in 23 fixtures away to Southampton this weekend, but are priced at 31/20 (2.55) to bounce back with a big win over their local rivals.
None of the last four meetings between this pair have resulted in draws, but you can get odds of 13/5 (3.60) on this one going into extra-time after a deadlocked 90 minutes.
Eric Dier is out until January after undergoing surgery to remove his appendix, joining Juan Foyth, Davinson Sanchez, Victor Wanyama, Serge Aurier and Mousa Dembele on the sidelines.
The Gunners are also facing a defensive crisis, with Hector Bellerin out after coming off injured on Sunday. Rob Holding is ruled out for a while after undergoing surgery on his knee, while Konstantinos Mavropanos remains injured and Shkrodan Mustafi faces a late fitness test.
Considering the defensive absentees at both ends and the amount of goalmouth action on display when this pair met just a few weeks ago, entertainment looks more than likely on Wednesday.
Having conceded three times against a hardly prolific Southampton at the weekend, Arsenal certainly cannot be expected to contain a visiting attack that has not failed to score in 14 away games this season.
However, Emery's team have only been outscored by Manchester City in the Premier League this campaign, and make odds of 4/5 (1.80) look like solid value on them joining Tottenham on the scoresheet in another match that features at least three goals.
Odds correct at the time of writing. Please gamble responsibly.