Cenk Tosun is the third substitute to be substituted in a PL match this season

Cenk Tosun is the third substitute to be substituted in a Premier League match this season - with all three instances being Everton players (also Moise Kean vs Man Utd & Alex Iwobi vs Man City). 

Tosun was brought on in the 11th minute of the game and was brought off in the 80th minute. In Everton's last game, Moise Kean was brought on 70th minute and was brought off in the 89th minute. In their 1-3 defeat to Man City, Iwobi was brought on in the 7th minute and was brought off in the 74th minute.