Southampton make a Friday night trip to Sheffield Wednesday to kick-off the new Sky Bet Championship season, with Leeds hosting Cardiff and Leicester playing Coventry on the opening weekend.
The Saints are back in the second tier for the first time since 2012 following their Premier League relegation and their trip to Hillsborough to play promoted Wednesday lifts the curtain on the new campaign on Friday August 4.
A Sunday triple-header on August 6 will see Leicester, relegated from the top-flight on the final day, host Coventry, who lost last season's play-off final to Luton, at 12pm.
Leeds, who also came down, host Cardiff at Elland Road at 2.30pm, before Sunderland take on Ipswich Town at 5pm.
There are eight games, all at 3pm, on Saturday August 5 as the Championship season begins in earnest.
Plymouth Argyle, champions of League One, open up at home to Huddersfield Town. Middlesbrough, who reached last season's play-offs, entertain Millwall.
Blackburn Rovers play West Bromwich Albion, Norwich are at home to Hull, Queens Park Rangers host Watford, Stoke City take on Rotherham, Swansea face Birmingham and Bristol City welcome Preston.
Only the precise kick-off times for the opening weekend have been confirmed for the moment, with subsequent rounds of fixtures all subject to change for Sky Sports coverage.
Saints confirmed the appointment of former Swansea boss Russell Martin as their new manager on Wednesday.
The second weekend of the Championship season will see Leeds make the trip to Birmingham, Leicester head to Huddersfield and Southampton host Norwich.
The Boxing Day schedule sees Leeds travel across the Pennines to Preston, Leicester head to Ipswich, Southampton host Swansea and West Brom take on Norwich.
The season will conclude on Saturday May 4, with Leeds playing host to Southampton at Elland Road.
Leicester round off their campaign at home to Blackburn, while Middlesbrough play Watford at the Riverside Stadium and Sunderland entertain Sheffield Wednesday.
Leeds are back in the Championship after three Premier League seasons, while Leicester spent nine years in the top-flight.
Early bookmaker odds have the relegated trio as favourites to bounce straight back into the Premier League, with Middlesbrough, Watford and Norwich also fancied.
Plymouth will play Championship football for the first time since the 2009-10 campaign after they secured the League One title with a remarkable 101 points by winning at Port Vale on the final afternoon of last season.
Ipswich also secured automatic promotion having amassed 98 points, with Wednesday beating Barnsley in the play-off final to get back to the second tier.
The Tractor Boys had been away from the Championship for four seasons and their return sees the resumption of the East Anglian derby with Norwich.
Wednesday made the shock announcement this week that their manager Darren Moore had left the club by mutual consent weeks after securing promotion.