Mario Rui and Simone Verdi have been ruled out of Napoli’s Europa League last-32 first leg against FC Zurich on Thursday.
Napoli’s official website confirmed Rui was carrying a hamstring strain and Verdi had bruising to his right knee.
They join Amin Younes and Raul Albiol on the treatment table, while Marek Hamsik again misses out as his closes in on a transfer to Dalian Yifang.
Napoli squad to face Zurich: Meret, Ospina, Karnezis, Maksimovic, Koulibaly, Ghoulam, Luperto, Malcuit, Hysaj, Chiriches, Fabian, Zielinski, Allan, Diawara, Mertens, Callejon, Gaetano, Milik, Insigne, Ounas
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