In what is expected to be the most entertaining Premier League game of the weekend, West Ham are hosting leaders Manchester City on Sunday at the London Stadium.
The Sky Blues will travel to the English capital without defenders John Stones, Kyle Walker and Ruben Dias, all of whom are out injured for the remainder of the season.
Meanwhile, both Fernandinho and Aymeric Laporte picked up injuries in Manchester City's 5-1 win away at Wolverhampton Wanderers on Wednesday and they are doubtful for this game.
This means that holding midfielder Rodri could drop at the back and play alongside Nathan Ake, who has just recovered from injury.
As for West Ham, Angelo Ogbonna is out injured for the remainder of the season and Said Benrahma is an injury doubt, but Michail Antonio and Craig Dawson are fit to play.
A win would bring Manchester City one step closer to winning the league, with the Sky Blues currently sitting three points above second-placed Liverpool. Meanwhile, seventh placed West Ham have yet to secure European qualification, but they could do so if they beat Pep Guardiola's side.
West Ham vs Manchester City predicted line-ups
West Ham's predicted line-up (4-2-3-1): Lukasz Fabianski; Vladimir Coufal, Craig Dawson, Kurt Zouma, Aaron Cresswell; Declan Rice, Tomas Soucek; Jarrod Bowen, Manuel Lanzini, Pablo Fornals; Michail Antonio.
Manchester City's predicted line-up (4-3-3): Ederson; Joao Cancelo, Rodri, Nathan Ake, Oleksandr Zinchenko; Kevin De Bruyne, Ilkay Gundogan, Bernardo Silva; Gabriel Jesus, Phil Foden, Jack Grealish.
When does West Ham vs Manchester City start?
The game between West Ham and Manchester City kicks off at 14:00 BST, the local time in London. That makes it a 15:00 CEST kick-off for those in Spain, while fans in the United States will find the game starting at 09:00 ET or 06:00 PT.
Where to watch West Ham vs Manchester City
Football fans in the United Kingdom can tune in to watch West Ham vs Manchester City on Sky Sports Main Event and on Sky Sports Premier League. In the United States, it will be shown on USA Network, Telemundo and Telemundo Deportes En Vivo.