The former Gunners front man is in the United starting XI against a much-changed Arsenal lineup
Alexis Sanchez starts for Manchester United against former club Arsenal for the first time at Old Trafford on Sunday.
The Chile international moved to United in January as part of a swap deal, with Henrikh Mkhitaryan moving the other way, and will take to the field against the Gunners in Arsene Wenger's final visit to the Theatre of Dreams as Arsenal boss.
Arsenal, meanwhile, have made a host of changes, ahead of their clash Atletico Madrid in the second leg of the Europa League semi-final this week.
United make just one change to the XI which beat Tottenham Hotspur in last week's FA Cup semi-final, with Victor Lindelof stepping in to replace the injured Phil Jones at centre-back.
That means there is again no start for either Anthony Martial nor Marcus Rashford in the forward line as Jose Mourinho sticks with Jesse Lingard, Romelu Lukaku and Sanchez in a three-man attack.
Mkhitaryan returns for Arsenal following a knee injury to make his first appearance at Old Trafford since his winter move.
Elsewhere there are starts for Konstantinos Mavropanos, Reiss Nelson and Alex Iwobi as Wenger makes a total of eight changes from Thursday's 1-1 draw with Atletico.
Manchester United XI: De Gea; Valencia, Lindelof, Smalling, Young; Herrera, Matic, Pogba; Lingard, Lukaku, Alexis. Subs: Pereira, Rojo, Fellaini, Mata, McTominay, Martial, Rashford
Arsenal XI: Ospina; Bellerin, Chambers, Mavropanos, Kolasinac; Xhaka, Maitland-Niles; Iwobi, Nelson, Mkhitaryan; Aubameyang. Subs: Cech, Holding, Monreal, Osei-Tutu, Willock, Welbeck, Nketiah.
deeceiknps
1
miss miss is good to go is good
Paoginpu
1
R WE TO WAIT THE REAL SANCHEZ......😂Useless fellow
Fozbemrtu
2
Alax is nothing
emondorock
1
If man u cant beat this arsenal team by 4 goals they are goinf nowhere next season
The-LeoMessi-CULE123
4
He is already showing his worth in the match!!
Harryjaden
1
I don't know what he'll do it but one thing is for sure he's not the next Mo Salah
frank_leo
2
Facing Alexis will be strange
marlyn02
2
win win win
TSRai
3
Sanchez shall go further far
TSRai
3
leave aside old memories and get on with new experience with MU
Lordpizarro
0
He will score
bulemooe
0
Has scored 3 goals since he joined including 1 penalty. Right choice
uglyboy
0
He wants money thats what he wants money
offlinea
0
only bought to try and get one over on city, only succeeded in getting one over on himself.
luxurious
0
He's not been at his best in some games, and yet still been involved in 8 goals in 14 games. He'll benefit from the defence and midfield being stronger and more settled next season. Better base to work from.
Hanhaar
0
Best player in the prem.
updatea
0
We needed that bit of experience, at 30 yr old this year he should have.
Budbcdkoty
1
man u takes the day..3 goals are coming
feaelmt
0
haaaaaah well win
Rubbeiklru
2
With this formation Gunners have already lost
tozadinry
1
lets see how arsenal react