The visitors have picked up just eight points from seven Bundesliga games on the road this season and face a daunting task at the Allianz Arena
Many expected the Bundesliga to be another procession for Bayern Munich.
The Bavarian giants romped to another German top-flight title by an impressive 21 points last season. This term though, things haven't been straightforward for Nico Kovac's men.
Bayern trail Borussia Dortmund by 11 points but can close that gap after the league leaders lost 2-1 at Fortuna Dusseldorf earlier this week.
888Sport make the hosts just 1/3 (1.33) to come out on top as they host RB Leipzig. While that's unlikely to tempt many punters into siding with the Bundesliga champions, there is reason to suspect they'll be able to win by a more emphatic margin.
Leipzig are 7/1 (8.0) underdogs for this game with the draw available at 21/5 (5.20).
It's understandable to see such a big price on the visitors given their struggles away from home this season. Ralf Rangnick's side have picked up just eight points in seven league games on the road.
Those results include a 3-0 defeat at Freiburg last time out and a 4-1 thrashing at the hands of Dortmund.
While Bayern's form isn't as impeccable as one might expect, Kovac's men should have enough to record a win over a travel-sick Leipzig outfit.
With that in mind, the 22/25 (1.88) on offer from 888Sport about Bayern to win the game by two clear goals looks the way to go. Both league meetings between the pair at the Allianz Arena have seen this bet land and Leipzig are yet to find the net at this venue.
Having won their previous three Bundesliga matches by an aggregate score line of 9-1, there's plenty to like about backing another wide-margin victory for the defending champions on Wednesday night.