Chelsea interim boss Calum McFarlane confirmed Estevao has been ruled out for the remainder of the season, while his World Cup participation is in doubt.
The Brazilian was forced off in the first half of Chelsea's defeat to Manchester United last weekend after a sprint down the wing.
Estevao has played 36 games across all competitions in his first campaign with the Blues, scoring eight goals and providing three assists.
He has directly contributed to three goals (two goals, one assist) in as many FA Cup games this term as Chelsea prepare to take on Leeds United in the semi-final on Sunday.
However, the concern for the Blues, and Brazil, is that the 19-year-old also missed games in December and March with muscle injuries, in addition to his current issue.
Brazil's World Cup campaign begins on June 13, when they take on Morocco in Group C.
"Estevao, unfortunately, won't play for us this season," said McFarlane. "He's going to be out for a little bit of time. That's really unfortunate, especially for someone so young and so talented.
"But we're here to support him and be around him.
"I'm not sure [about the World Cup], if I'm honest. I just know he won't be available for us. I'm sure he's very hopeful he can make the World Cup, but I don't know on that."
Chelsea have won just one of their last eight games in all competitions, leading to the dismissal of Liam Rosenior, though that victory came in the FA Cup.
They thrashed Port Vale 7-0 at Stamford Bridge, while they have also defeated Wrexham, Hull City and Charlton Athletic in the competition this season.
Chelsea have reached the FA Cup semi-finals 28 times, with only Manchester United (32) and Arsenal (30) reaching the final four on more occasions.
McFarlane believes Chelsea will show their true quality at Wembley Stadium after a dismal display against Brighton on Tuesday.
"The performance wasn't good enough. Everyone associated with the club knows that, the players know that," added the interim boss.
"I thought Brighton were very good on the night, and I don't think they got enough credit. They're a really good side with a really good manager.
"Our performance wasn't good enough, and we're going to address that on Sunday and make sure we perform to the level we know this group is capable of."
roucdemoru
1
I which you quick recovery and match fitness in Jesus name.
Kancimotu
0
this use to be Neymar time to fake injury just to play world cup
he's really injured
Biodilmnyz
1
Quick recovery 💙
Vizaeinos
1
WHAT IS GOING ON!!!! Yamal, Guler, Militao now Estevao
I missed the news about guler, now I understand why he didn't play, too bat to football, the boys are being overused the fixtures are just too much
Wocceilp
1
this use to be Neymar time to fake injury just to play world cup
greenshoes
0
flop
Habcimprt
0
sorry my champion quick recovery
latcelmoyz
1
Ccvb
LilMoneyMoneyMaker
0
Hmmm!this hamstring injury is really destroying the career of the young players to be come oo,this is so bad when I heard a young talented players got a hamstring injury 😔😞
Hikcdeiot
1
Chelsea club Doctor if fake also
Jiydeorstz
2
gnabry for Germany.then who will be the stars left for the world cup
Coyblopt
1
Wish you a speedy recovery lad. UEFA and FIFA should cut down some of these congested fixtures to protect players and their welfare
wowadrsyz
0
players will start to fake injuries just to participate in the world cup the schedule is too much fifa need to reduce the games or remove certain unnecessary national teams calendar games like friendlies
AlwaysSoccer
0
The young prospects everyone were looking forward to seeing in the WC, seems a doubt and it's such a shame. Speedy recovery to them all
Elishaphiri
2
This is so sad wishing him a quick recovery [Sadtolook]
Trevorn
0
WHAT IS GOING ON!!!! Yamal, Guler, Militao now Estevao
Hritangshu93
2
First Yamal then Estevao......this is bad.....hope they are ready for WC