Aoba Fujino's first-half brace set Manchester City on their way to a first Champions League win of the season, as they came from behind to beat Inter 4-1.
With a huge top-of-the-table clash with Chelsea coming up in the Women's Super League, Andree Jeglertz opted to shuffle his pack in Italy, with Khadija Shaw among the City substitutes.
And though the visitors carried the greater threat in the early stages, they conceded against the run of play in the 24th minute. Ivana Andres curled a delightful ball into the City area from the left-hand side, and Elisa Bartoli's glancing header nestled in the right-hand side of Ayaka Yamashita's goal.
City were not even behind for 10 minutes, though, as England international Laura Blindkilde Brown split the Inter backline with a glorious, left-footed through-ball, and Fujino finished confidently.
Mary Fowler dragged an effort wide on the turn as City dialled up the pressure, but she was involved when the visitors went in front in the 44th minute. Cecilia Ran Runarsdottir smothered Fowler's shot after Iman Beney showed great pace to break down the right flank, but Fujino was there to put the rebound away.
Fujino was, along with Jade Rose, withdrawn by Jeglertz at half-time, perhaps with one eye on that upcoming trip to Stamford Bridge, and Yamashita had to turn Haley Bugeja's curler wide soon after the restart.
But City did not let their performance levels drop, going 3-1 up when Kerstin Casparij turned on Sam Coffey's pass and whipped a neat finish into the near corner after 56 minutes.
It was 4-1 with 20 minutes to play, with Grace Clinton prodding Lauren Hemp's hanging cross home at the far post, and though Inter had some bright moments late on – including Michela Cambiaghi forcing Yamashita into another tremendous save – they were unable to eat into City's lead.
Elsewhere on Tuesday, there were victories for Real Madrid, who thumped Paris FC 3-0 with goals from Arianna Caruso, Lineth Beerensteyn and Linda Caicedo, and Bayern Munich, who held off Paris Saint-Germain for a 2-1 win following a Katarzyna Kiedrzynek own goal and a strike from Klara Buhl. Paulina Dudek scored a penalty for PSG.
Scintillating City up and running
Having won each of their first five group-stage matches in the Champions League, City had endured a four-game winless streak in such contests (D3 L1), with their slow start to the 2026-27 edition seeing them lose ground on the top four.
However, this was as comprehensive a victory as Jeglertz could have wished for, particularly after City rested several key players and fell a goal behind.
They ended the game with 21 shots and 3.4 expected goals (xG), compared to Inter's figures of 16 attempts and 1.1 xG.
And Jeglertz did not even have to call upon Shaw, who was an unused substitute after scoring in back-to-back Champions League games, and could also limit the gametime of Fujino, Hemp, Rebecca Knaak (45 minutes each) and Yui Hasegawa (15 minutes).
Having watched Chelsea labour to a goalless draw in their own Champions League match on Tuesday, versus Swedish side Hacken, City will be feeling very confident about their chances on Saturday.