Real Madrid can seal the LaLiga Santander title by beating Villarreal on Thursday and Zinedine Zidane is expected to name a strong line-up for the match against the Yellow Submarine.
Thibaut Courtois will be between the posts with Dani Carvajal, Raphael Varane, Sergio Ramos and Ferland Mendy in defence.
A three-man midfield will consist of Casemiro, Toni Kroos and Luka Modric, who will play behind Eden Hazard, Marco Asensio and Karim Benzema.
Meanwhile, Villarreal, who are in a great a shape after the pandemic enforced break, are aware that they can clinch European qualification on Sunday against Eibar, if they fail to get something out of the match at the Estadio Alfredo di Stefano.
Probable line-ups
Real Madrid: Thibaut Courtois; Dani Carvajal, Raphael Varane, Sergio Ramos, Ferland Mendy; Casemiro, Toni Kroos, Luka Modric; Eden Hazard, Karim Benzema, Marco Asensio.
Villarreal: Sergio Asenjo; Mario Gaspar, Raul Albiol, Pau Torres, Alberto Moreno, Manu Trigueros, Andre-Frank Zambo Anguissa; Moi Gomez, Javi Ontiveros, Samuel Chukwueze; Gerard Moreno.