The Gunners are looking to record consecutive victories for the first time since the first week of 2019 when they host the struggling Saints
Having avoided a scare in Europe during the week, Arsenal return to domestic action on Sunday against Southampton as they look to enhance their chances of a top-four finish in the Premier League.
The Gunners have slumped to fifth in the table and sit a point behind Manchester United, but Unai Emery's men are not giving up on sealing a spot in next season's Champions League.
Emery's team managed to come from behind against BATE Borisov to progress to the Europa League last-16 during the week and will be aiming for another positive result when they host a Saints team trying to claw their way out of the bottom three.
Live Stream & How To Watch
In the United States (US), the game can be streamed on NBC Sports Gold.
The game will not be broadcast live in the United Kingdom, but it can be followed live on Goal by clicking here.
Squads & Team News
Rob Holding, Danny Welbeck and Hector Bellerin are still out injured, but Ainsley Maitland-Niles needs to be assessed after coming down with illness.
Laurent Koscielny was substituted early against BATE because of a slight injury concern, but Unai Emery said the centre-back could be available for Sunday's game.
Possible Arsenal starting XI: Leno, Lichtsteiner, Sokratis, Mustafi, Kolasinac, Xhaka, Guendouzi, Mkhitaryan, Ozil, Iwobi, Aubameyang.
Danny Ings, Mario Lemina and Michael Obafemi are still missing through injury, while Scottish midfielder Stuart Armstrong could be back in the team after missing the recent defeat to Burnley.
Possible Southampton starting XI: McCarthy, Vestergaard, Bednarek, Stephens, Valery, Hojbjerg. Ward-Prowse, Romeu, Bertrand, Long, Redmond.
Betting & Match Odds
Arsenal are favourites at 1/2 with bet365. A draw is priced at 15/4, while a Southampton victory can be backed at 6/1.
Click here to see more offers for the game, including goalscoring markets, correct score predictions and more.
Match Preview
Arsenal may have secured their place in the last-16 of the Europa League this week, but that will do nothing to ease the pressure on Emery's men as they look to salvage their Premier League campaign.
The inconsistent Gunners have slipped a point behind fourth-placed Manchester United in recent weeks and will be determined to prove they are growing in confidence by recording back-to-back wins for the first time since the start of January.
Mesut Ozil was back dictating his side's attacks against BATE on Thursday after being left out of Arsenal's last three matches and Emery could let the midfielder to keep his place against the Saints.
The German's future in north London looks uncertain amid reports the club want to offload him in the next transfer window, but team-mates Alex Iwobi and Sokratis Papastathopoulos believe the Gunners desperately need him.
"We know what Mesut is like because we see him in training every day," Iwobi told reporters after Thursday's victory.
"He's world class. We scored three goals as a result of him playing. I know if I make a run he has the vision to find me. Hopefully he can keep on playing."
Sokratis added: "Mesut is a fantastic player and when he is fit he is one of the most important players of the team.
“Of course when something is not going good, everybody is there to criticise but we have to see also what Mesut did in the last years for this team.
“All the team, all the players are behind him and we need a good Mesut to go [forward] because we know that he is very important for us."
deebeiou
0
Why not aaba
deebeiou
0
Why not ayba
veyaklmnpu
1
Should play Ozil[cup][cup][cup][cup][cup][cup]
maybesy
1
the team can beat Southampton
sathyanjishnu
0
which site I can watch this in UAE..plz guys
Germany_Özil10
1
Hope Ozil will play.
kamaldin
1
This will be my first match on Emirates Stadium. #COYG
Have a good time . It's always my dream to watch a game at THE EMIRATES .
Humancalculator
3
Malpacinons
2
Going to be the first game i miss this season. Hopefully the boys get the job done. We really need to get 3 points and build some confidence before we go to the toilet. COYG
Samuleley
1
Need to start ozil and play quick fast build up. Can't cross against southhampton. 4231 like last game but less crossing more playing through the middle. Iwobi/Suarez and Mkhi need to come narrow more. AMN needs to start right back as well as Guendouzi and Torreira. They will press and I don't think Xhaka is ready just yet. Maybe bring him on last 15-20 mins depending on the game.
Barnhart
0
Would like to see Carl start at RB in this game. Ozil deserves to keep his spot but want to see him play in the number 10 role behind Laca. Auba and Iwobi on the wings. Torreira and Guendouzi in the middle of the park. Most win game for us today! No messing around let’s get down to business early and put this to bed by halftime. If United don’t beat Liverpool we can move into the top 4 with a W! COYG!
kamaai
0
we seem to have mixed results against the saints, really need a convincing win against them today but knowing our defence it could go either way
Brown83
0
Very important game, if liverpool beat man u we're back in top 4! And then if we beat man u that gives us a safe amount of distance from them.
Derrickse
0
think Ozil will start again. expecting a very scrappy win against Soton doe, they've always been tough for us
Chinyerers
0
Hope Ozil starts to continue on his good performance this week.
ausoga
1
this is a classic setup lol. we just need to do our job and win this game because i think liverpool will do us a favour. laca should start & maybe bring auba at the 60 min mark to get him some run against a tired side. AMN should be RB if healthy, can't risk licht against a PL side. And finally ozil pls unai
CEO222
0
Southhampton away turned out to be a major turning point. This one will be too.
championon
0
I think this would be a good game to start Dennis Suarez in place of Mikhi. He should be given a chance in the starting line-up to show what he is capable of.
pinkmans
0
Ramsey should start. He needs to get back to match fitness for Spurs and United.
Rundlsty
0
congrats
GEMfans
0
Our club has the most random records broken against teams like these... commentators are like x player has never scored for his club until today... a 35 yard weak foot volley against arsenal and our statisticians are telling us that the team have never won away at arsenal since world war 1 but today they have done it.
Santiag
0
Great start to the weekend ! Burnley !!!
educate
0
Time to get some revenge we'll batter them 3-0, bloody hate Liverpool B
Olivekiss
0
Ozil plz Emz Let the boy play
interface
0
We only have Spurs at Wembley and United home to play among top 6 so we really need to beat these mid and bottom teams now.
Elsamek
1
This will be my first match on Emirates Stadium. #COYG
yumbcdpryz
1
arsenal best lineup against Southampton
Bibadekmuy
1
I want this
Juneiknrsu
0
Arsenal will win handsomely if Ozil plays the full match today.
Zapcdkor
0
best squad against Southampton
YashrajNagarwal
2
correct lineup aganist southampton
Zapcdkor
1
Arsenal vs Southampton
posdinptz
1
yahcelnopt
2
Emery is failing the gunners by playing Guendouzi and leaving the best players in midfielder he should start from the bench