The return of the Copa del Rey presents an opportunity to Ernesto Valverde that he cannot pass up - that is to give playing time to players that have not been relied on this season.
Top tier sides are favoured by the format of the competition to the detriment of their smaller opposition, which plays into the hands of Valverde as he looks to change things up in his starting XI.
There is however a requirement that there are always at least seven first team players on the pitch, so the possibility of Barcelona filling their team with youth players is out of the question.
Wednesday evening then should see players like Denis Suarez, Malcom, Sergi Samper or Carles Alena take a leading role in the team and stake a claim for greater importance in Valverde's plans going forward.
Deniz Suarez went down with injury in preseason and his recovery took slightly longer than expected but now he is back and ready to push for a place in the side.
Samper, meanwhile, has never been counted as a real option this season and the idea is for him to leave the Camp Nou as soon as he can and the Copa could be the perfect shop window for him.
Malcom is another in a strange situation and he is one of the new arrivals having arrived in a controversial 41 million euros move, with Barcelona swiping him out of the hands of Roma and Monchi.
To date, the Brazilian has only played 26 first team minutes and should he not play in midweek, the problems will appear deeper than they have until now.
Carles Alena's preseason performances suggested that he was ready for first team action but an injury dictated that he would remain in the youth team for a little longer.
The biggest doubt around the game is what Barcelona will do defensively and Valverde himself remains unconvinced, with Thomas Vermaelen and Samuel Umtiti's injuries leaving him with something of a handicap.
Since the draw, those in Leon have not stopped talking about the game and Cultural had to overcome three preliminary rounds to reach this point.
They want to enjoy the occasion, while also being keen to show themselves in a good light.
Henryrukis
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Barcelona is a great team and they have great talent in the youth ranks. if these young players leave for other clubs ,they will all be a starter in.but because it's Barcelona, they need to bear the situation. players like Suarez, Malcolm, dembele, Elena, and so on.. they are very good players and Barcelona should value them. don't forget it is the lamasia of then that Is still rulling the football world today.