No.21 vs No.22: Which midfield pair can create more chances this season?

Hello AFers, welcome to our 'Numbers Battle', just feel free to leave your opinions.

We have formed two sides in the battle for a certain topic.

Side 1: Frenkie de Jong and Milinkovic-Savic in No.21

Side 2: Isco and Ziyech in No.22

Which pair can create more chances this season?