Tuesday night won't be the first time Lionel Messi and David Ospina's paths have crossed in their careers - far from it.
The pair have history with both their clubs and national teams, bringing a South American taste to Barcelona's Italian job.
Perhaps one of their most memorably encounters came in the 2015 Copa America, when Colombia played Argentina in the quarter-finals.
Ospina stopped everything that Messi threw at him, including a header from point-blank range, before Argentina finally prevailed on penalties en route to the final.
Having lost the personal duel that summer, Messi was back on top the following year, firing a freekick past Ospina in World Cup qualifying.
Messi and Ospina also met in the knockout stages of the Champions League that year as Barcelona were drawn against Arsenal.
Ospina didn't feature in Barcelona's first-leg victory but did play at the Camp Nou and produced an impressive display to keep the score down to 3-1.
Now, at the Stadio San Paolo, Ospina's Napoli play host to Messi's Barcelona in the first leg of their Champions League last-16 tie.
dculest
305
BREAKING NEWS : If you see this "young" player known as Lionel Messi anywhere in Italy streets, please call the police right away. He has recently been infected with two highly dangerous viruses: The CoronaGoals and the CoronaAssists. If he goes away without any treatment, no team in the world would be willing to play against HIM. 😂😂😂
HAH224
277
Honestly Im a Madrid fan but Messi is a beast