England will host Italy in an international friendly at Wembley on March 27 as part of their preparations for Euro 2020.
The fixture, which has been named The Heads Up International in support of The Duke of Cambridge's Heads Together mental health initiative, will be the first of four warm-up matches for the Three Lions ahead of the tournament.
England also face Denmark at Wembley on March 31 before travelling to face Austria in Vienna on June 2.
Gareth Southgate's side will then take on Romania in their final warm-up match on June 7, at a home venue outside of London, which is still to be confirmed.