Ole Gunnar Solskjaer returns to the scene of his greatest triumph on Tuesday night, aiming for a repeat of the 1999 Champions League final when Manchester United take on Barcelona at Camp Nou in a blockbuster quarter-final second leg.
United's recently-appointed manager scored a memorable late goal against Bayern Munich to win the second of three European Cups for United, and his side require a result of similar magnitude two decades on as they trail Barca 1-0 from the opening 90 minutes.
Barcelona predicted line-ups: Ter Stegen; Semedo, Pique, Lenglet, Alba; Rakitic, Busquets, Arthur; Messi, Suarez, Coutinho
The hosts gave Messi, Sergio Busquets, Ivan Rakitic, Suarez and Gerard Pique the day off for their trip to Huesca, with the latter two suspended.
Messi suffered a facial injury against United but has been given the all clear to continue playing, while Rakitic has been struggling with illness but should be OK by Tuesday.
Despite having a mixed time of things since making the switch to Camp Nou 15 months ago, Philippe Coutinho has been tipped to retain his place in the forward line as Ousmane Dembele is lacking match fitness.
Suarez should also start, though he has had more shots without finding the net than any other player in the Champions League this season (33).
Manchester United predicted line-ups: De Gea; Dalot, Lindelof, Smalling, Darmian; McTominay, Fred, Pogba; Rashford, Lukaku, Martial
Solskjaer made five changes to his side against West Ham on Saturday, with kickoff coming just 72 hours before their trip to Catalonia, and he all but confirmed after the match that Scott McTominay and Marcus Rashford will return on Tuesday night.
Nemanja Matic and Ander Herrera have not featured for United since the end of March, so Solskjaer may well have to stick with Fred in a weakened midfield three.
Matteo Darmian and Antonio Valencia have also been sidelined, as have Eric Bailly and Alexis Sanchez, but Solskjaer has no fresh injury concerns to contend with, though Shaw will be absent through suspension.