Allan, Kostas Manolas and Amin Younes are out of the Napoli squad to face Lecce on Sunday.
The Partenopei are fresh from a spectacular 2-0 Champions League victory over Liverpool in midweek.
Manolas picked up a knock during that game and is, therefore, rested as a precaution with Younes, while midfielder Allan is suffering from flu symptoms.
It’s reported the Brazilian was already unwell before the Liverpool match and almost didn't play.
Napoli squad for Lecce: Callejon, Di Lorenzo, Elmas, Fabian Ruiz, Gaetano, Ghoulam, Hysaj, Insigne, Koulibaly, Karnezis, Llorente, Lozano, Luperto, Maksimovic, Malcuit, Mario Rui, Meret, Mertens, Milik, Ospina, Zielinski