KOBBIE MAINNO, Ezri Konsa and Morgan Gibbs-White have all withdrawn from England's upcoming Uefa Nations League squad.
The Three Lions host Greece at Wembley on Thursday, before heading to Finland on Sunday, in Lee Carsley's second round of fixtures.
The trio drop out after sustaining injuries for their respective clubs over the weekend in what is a triple injury blow for Carsley's new-look side.
Konsa, 26, suffered a hamstring injury and left the field just 12 minutes into Villa's goalless draw with Manchester United.
And Gibbs-White, 24, was removed after 76 minutes of Nottingham Forest's 1-1 draw at Chelsea.
But Mainoo played 85 minutes at Old Trafford on Sunday before he was replaced by Casemiro.
It comes as a blow for under-fire boss Erik ten Hag who also lost the services of Harry Maguire against Villa.
Mainoo has been carrying a knock for some time.
The Man Utd star was subbed off shortly before half-time during Ten Hag's 3-0 demolition by Tottenham a fortnight ago.
He travelled to Portugal with the Red Devils on Thursday as they drew 3-3 with Porto, but missed the game with a minor injury.
Meanwhile Carsley handed Konsa a starting role when the Three Lions beat Finland 2-0 at Wembley on 10 September.
Gibbs-White made his senior debut for England from the bench during their 2-0 victory against the Republic of Ireland on 7 September.
Forest manager Nuno Espirito Santo also suggested the prognosis on Gibbs-White is unclear until they further investigate on Monday.
All other 22 players are at St. George’s Park with no further additions planned at this time.
Harry Kane was a doubt too, but he has since been cleared to play after arriving to St George's Park earlier today.
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Pohadklrtu
0
Pohadklrtu
1
nehbelmopr
0
weoeikptz
1
bellingham and gallagher
GavivinaGator
0
Saka always in the Squad
Memaceiklu
0
Overrated
ColinsGooner
1
So are they all faking Injuries,Why do haters say Havertz faked his injury but when it's players from your team it is well
PaulPuspanathan
0
stupid international break. Saka and Rice pls pull out
Jucabeiksy
0
lazy guy doesn't chase back ball run like tortoise 🐢
EmmanuelsonAbubakar
2
after Ten Hag noticed that he was out of the squad, and said to his master I'm the one that can make players. this is why I'm asking man united to give me time so I can build the team with Dutch 🐐 goat and his master ask why bring in dutch players he said because untied is the only dutch team in the EPL
SGTSingam
1
Meanwhile at Manchester United, please stop these Vawulence on Ten Hag
Fawbikoruy
2
The only player i like at united
Shmonny
0
Terrible players never get ACL injury.
AlvynSserugga
1
Manchester United are faking injuries so they can reserve their players for more draws after the international break😂😂😂
tenlmntuz
1
to replace james maddison
Budabcepsy
1
Where is Tomori and Ben white 🤔
Wuwdelnpsz
0
Don't know why even dea staging this nations league coz few players want 2 participate
Money is the only reason. IMHO
Vicsammy
0
Garnacho n Mainoo injured, Erik in hell🤦♂️
bamadiloty
5
I am a Liverpool supporter, I loved the way this boy played last year but this year his standard has gone down, I think Ten Hag is not managing the time for this boy, he is still young and he can’t play all games
chizzyice
1
Manu players are pretending to be injured only for Ten hag to be sack
Zezesol400
2
Don't know why even dea staging this nations league coz few players want 2 participate