Danny Rose is a doubt for England’s double-header against Spain and Croatia after becoming the latest Tottenham player to sustain a muscular injury.
England medics will assess the left-back’s groin injury before making a decision on whether he can remain with the squad.
Rose limped off during the closing stages of Spurs win over Leicester on Saturday.
Leicester’s Ben Chilwell, who made his international debut against Switzerland last month, is in line to replace Rose if fails to prove his fitness.
Rose joins team-mates Christian Eriksen, Mousa Dembele, Jan Vertonghen, Dele Alli and Serge Aurier in suffering with muscular problems amid concerns manager Mauricio Pochettino’s punishing training sessions are taking its toll on players who played at the World Cup.
Elsewhere, there are fitness concerns over Burnley defender James Tarkowski ahead of the forthcoming UEFA Nations League fixtures.
Brighton defender Lewis Dunk has been watched extensively by England over the past 18 months is set to be drafted into Gareth Southgate’s party as a result.
MailOnline exclusively revealed on Friday that Dunk has signed a new five year deal with the Seagulls and that he was firmly on Southgate’s radar.
Wolves central defender Conor Coady is also on England’s watchlist.