Jurgen Klopp's side remain the only Premier League team with a 100 per cent record and the Reds should be backed to make another fast start
Chelsea dropped their first points of the Premier League season with a 0-0 draw against West Ham last weekend. Liverpool meanwhile, have secured victories from their each of their opening six matches and top the table.
The Blues won 2-1 at Anfield in the Carabao Cup midweek, which will surely boost their morale ahead of this clash at Stamford Bridge.
Despite home advantage Maurizio Sarri's side are underdogs at Stamford Bridge. The Blues are priced at 19/10 (2.90) with Betway who are 11/8 (2.38) about an away win. A draw is available at 5/2 (3.50) with the same firm.
Liverpool have only won one of their last eight away league games against fellow "big six" teams (D3 L4) although it did come at Wembley against Tottenham last season.
Both teams made a raft of changes for the cup clash but should be back to full strength on Saturday evening with top-flight points on the line.
Alex Oxlade-Chamberlain remains sidelined but Dejan Lovren made his first appearance of the season in the EFL Cup meeting on Wednesday and will push for a starting berth here.
The head-to-head record of these top-flight rivals suggests that they'll be tough to split.
Both teams to score is priced at just 11/20 (1.55) and that's understandable given Liverpool haven't kept a clean sheet against Chelsea in their last 14 league meetings.
However, despite the obvious amount of firepower both teams possess, such encounters are rarely ever the goal-fests punters might expect.
Four of the last seven matches between them in the Premier League have not only ended in a draw but by the exact 1-1 score line. Betway are 11/2 (6.50) about that trend being extended here.
It's difficult to ignore how well Liverpool have started the season. Not only are Jurgen Klopp's men the only team with a 100% record but their defence looks much improved compared to last term with the addition of Alisson.
The confidence and distribution the Brazil international brings has undoubtedly helped the Reds make the fast starts that been a feature of their matches so far. No side has scored more first half goals than Liverpool (10, level with Manchester City) in the current Premier League campaign.
Given that three of the four goals Chelsea have conceded in this competition so far have come before the half-time interval, backing Liverpool to score the first goal of the contest at 17/20 (1.85) with Betway looks the way to go.
Klopp's side have netted in the first 45 minutes of every league game so far this term and should be backed to break the deadlock once more at Stamford Bridge.