Manchester United midfielder Casemiro made two costly errors during the first half of Sunday's game against Liverpool.
The former Real Madrid star surrendered possession with a loose pass 10 seconds before Dominik Szoboszlai headed Liverpool 1-0 up in the 35th minute.
Casemiro was then tacked by Luis Diaz moments before the Colombian made it 2-0 seven minutes later.
Former United captain Gary Neville and ex-Liverpool skipper Jamie Carragher were part of the Sky Sports punditry team on Sunday and both men commented on Casemiro's mistakes.
Neville said: 'I have to say he's lost his confidence a little bit. For Casemiro, someone who has won Champions Leagues with Real Madrid, it can happen to you in games.
Carragher added: 'He's had such a great career and won everything you can possibly win, and it is a sad sight seeing what he's going through out there.'
Analysing Liverpool's second goal, Neville explained: 'Casemiro just gets shrugged off the ball. Never a foul, he just nicks it away from him.'
Carragher said: 'A poor pass can happen any time, but the second one, getting knocked over, he looks shattered as he's falling over.'
Casemiro did not return to the field after the half-time interval.
He was hooked ahead of the second 45 minutes as manager Erik ten Hag replaced him with 20-year-old Toby Collyer.