Man City will be desperate to return to winning ways, following the disappointment of drawing with Newcastle United, when they face Burnley on Tuesday.
City twice took the lead at St. James' Park but were twice pegged back by the Magpies and the 2-2 stalemate resulted in Premier League leaders Liverpool extending their lead on the Blues to 11 points after they won against Brighton.
The busy winter fixture list is now upon us and City have no time for respite as they travel to Turf Moor on what is set to be a bitterly cold evening.
With Liverpool not playing in the Merseyside derby until Wednesday a win is crucial for City to cut the lead and keep the title race alive but it won't be an easy task.
City only managed to scrape a late 1-0 victory on their last visit to Burnley and this time will have to do it without the suspended Ilkay Gundogan, as well as the injured Sergio Aguero, Aleks Zinchenko, Leroy Sane and Aymeric Laporte.
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The suspension of Ilkay Gundogan is almost irrelevant because Rodri would almost certainly have stepped in anyway, to add height to a small City team.
Fernandinho and John Stones shipped a couple of goals as centre backs on Saturday, but Nicolas Otamendi is a big option against the aerial threat of Burnley - but City's best bet is to control the game, as they did last year.
Benjamin Mendy should keep his place despite an awful display at Newcastle, simply because Angelino is too small for this game.
David Silva's ability to play two games in three days has to be questioned, and there is little to be lost by giving Phil Foden his chance - and Bernardo Silva's industry should get him the nod ahead of Riyad Mahrez.
Guardiola stopped short of saying he doesn't rate Nicolas Otamendi in his press conference when he was talking about why Fernandinho is consistently picked in defence but he needs to come back into the starting XI for City's trip to Turf Moor.
If ever there was a game that his physical presence is needed it's here and a return to the line up would also allow Fernandinho back into midfield to offer City's back line further protection.
Left-back is a tough one because Mendy hasn't been great but he remains a better alternative to Angelino so should start with Walker retaining his place at right-back.
Mahrez was poor against Newcastle and should drop to the bench and Guardiola has no other option than Jesus to lead the line with Aguero still out injured.
Even though Guardiola seems adamant that it is, it's clear that Fernandinho at centre-back just isn't working. Not only does it weaken the back-line as someone with little expertise is in the heart of it, it also hampers the midfield because its enforcer is missing.
Newcastle's equaliser came as a result of Fernandinho being caught out of position and giving away a cheap foul and Rodri has yet to adapt to Guardiola's team, making the foundations of the side shakey.
Stones and Otamendi might not be the best of partnerships but at least they are natural centre-backs and their reinstatement would see Fernandinho move back into the middle of the park, where his distribution, energy and defensive prowess has been sorely missed.
Mendy has also been struggling for form this season, which is understandable due to his lengthy time on the sidelines, but I'd swap him out for Angelino here.
The only other change to the team from Newcastle I would make is Bernardo coming for Mahrez but Jesus is lucky to keep his place, as he squandered several opportunities on Saturday - it wouldn't be surprising if Sterling is played as a striker again soon.