Arsenal pair Gabriel Jesus and Gabriel Martinelli have been given a starting role in a much-changed Brazil side for their final Group G encounter against Cameroon tonight.
Premier League rivals Ederson of Manchester City, Fabinho of Liverpool, and Manchester United duo Antony and Fred are all also included in the starting XI.
Tite's side need just one point to guarantee top-spot in the group, while Switzerland, Cameroon and Serbia remain in a fierce battle for the remaining place in the knockout stage.
Brazil have made a perfect start to their World Cup campaign as they look to win the tournament for the first time in 20 years, beating Switzerland and Serbia to qualify for the knockouts with a game to spare.
Tite, 61, has therefore been given the luxury of rotating his squad ahead of a last-16 showdown early next week, with Richarlison and Vinicius Junior afforded a much-needed rest.
Neymar remains the notable absentee, having suffered an ankle sprain in Brazil's opener against Serbia, with reports suggesting the initial hope the forward would be fit for the last-16 may in fact be false.
The 30-year-old can rest easy knowing that Brazil will reach the knockouts regardless of tonight's result, with Tite affording some of his more fringe players an opportunity to shine.
Included is veteran full-back Dani Alvez, who at 39 becomes the oldest captain in Brazil's World Cup history.
Confirmed Brazil XI: Ederson, Alves, Bremer, Militao, Telles, Fabinho, Fred, Rodrygo, Antony, Martinelli, Jesus.
Brazil, as stated, need only a point to confirm their place as Group G winners - and in doing so, they would play the runner-up from Group H, a place sealed by South Korea earlier today.
The match would take place on Monday, December 5 at Stadium 974, with kick-off at 7pm.
Should the improbable happen and Brazil finish in second, they would play against the Group H winners, being Portugal, on Tuesday, December 6 at the Lusail Iconic Stadium, with kick-off again at 7pm.