Manchester United and Newcastle are both in desperate need of three points on Saturday but all the omens point to a win for the home side.
Newcastle have a dreadful record at Old Trafford with the North-East side winning just once in their last 36 league visits to United.
That victory came during David Moyes' ill-fated reign when Yohan Cabaye scored in the 61st minute on December 7, 2013 to ensure Newcastle claimed their first league win there since 1972.
Newcastle, who beat United 1-0 at St James' Park in February, have not won back-to-back games against the Red Devils in 46 years.
Another stat that will not be good reading for Newcastle fans is the fact a Jose Mourinho side has never dropped a single point at home to their side.
Mourinho is under immense pressure at the moment with fans and players starting to turn on the Portuguese tactician but he will be delighted his side are facing Newcastle this weekend.
During his time at both Chelsea and Manchester United, Mourinho has won all six home games against Newcastle in the Premier League with an incredible goal difference of +16.
United hit four goals past Newcastle at home last November with Anthony Martial, Chris Smalling, Paul Pogba and Romelu Lukaku all getting on the scoresheet after Dwight Gayle netted an opener.
Mourinho will be hoping for a similar scoreline to silence his doubters ahead of the international break.
Despite United's poor form, the Old Trafford board remain fully behind the former Real Madrid and Chelsea manager.
Mourinho retains the backing of Manchester United's owners – although the next seven matches are key to his future.
United have not won at Old Trafford since the opening Friday of the Premier League season and Tuesday's 0-0 stalemate with Valencia was the latest setback in a disappointing start.
Mourinho's underperforming side entertain Newcastle this weekend and while a heavy defeat may prompt a different outcome, Sportsmail understands an upcoming schedule which includes fixtures with Juventus (twice), Chelsea and Manchester City will either seal his fate or buy him more time.
United are now without a win in four games across all competitions. That run includes an embarrassing exit from the Carabao Cup at the hands of Championship Derby County and a morale-sapping 3-1 reverse at West Ham United.