Timo Werner gave RB Leipzig a richly deserved first-leg lead in their Champions League last-16 clash with Tottenham as the Germans turned on the style in London.
The Bundesliga title-chasers spurned chance after chance, including three big opportunities in the opening 90 seconds, before Werner's penalty - his 26th goal of the season - early in the second half brought them a 1-0 victory.
Hamstrung by the absence of the injured Harry Kane and Son Heung-min, Tottenham had little bite in attack, with Lucas Moura ineffective in the central role, but they have a gem in Giovani Lo Celso who twice went close to an equaliser that would have flattered the hosts.
Tottenham's hopes of another run to the Champions League final look bleak, but Jose Mourinho must know his team could have been effectively out of this tie already ahead of the March 10 second leg in Leipzig.
Match Events
2' CLOSE! Angelino hits the post
Sanchez blocks Werner's low shot from inside the box but it goes to Angelino who blasts his effort into Lloris from a tight angle and it deflects onto the post and away.
Werner then has another close-range effort but he's flagged for offside.
8' Bergwijn's shot stopped by Gulacsi
Lo Celso feeds Bergwijn, who draws a smart stop from Gulacsi before Alli is flagged offside.
36' Great stop from Lloris!
Laimer threads it through to Werner in the box. The on-fire Leipzig striker has acres but delays too long, giving Lloris time to close the angle and parry the fierce strike to safety.
48' Lucas' shot stopped by Gulacsi
It's a lovely pass into the box from Aurier and Lucas clips it goalwards but Gulacsi is down well to parry it away.
58' Penalty Goal! Tottenham 0-1 Leipzig (Werner)
PENALTY TO LEIPZIG! Werner clips the ball into the box, where Laimer has made a darting run, and as the midfielder brings it down on his chest, Davies clatters into him.
Timo Werner steps up to take the spot-kick... and blasts the ball past Lloris.
It's low and past Lloris' right hand, ends Werner's run of five games without a goal and, most importantly, puts Leipzig one away goal to the good.
62' Another great save from Lloris!
Tottenham have got to remain disciplined at the back here, as Leipzig almost make it 2-0.
Angelino passes into the box, Werner steps over it and Schick fires at goal - but Lloris dives to his left to parry it away.
73' CLOSE! Lo Celso's free-kick hits the post
Lo Celso whips a bending left-foot shot at goal and it's a superb finger-tip save from Gulacsi, who pushes the ball onto the post!
So close to an equaliser!