The Parisians boss admits the club's fortunes this season rely heavily on their two stars thriving off each other
Speaking at a news conference on Friday, Tuchel confirmed both Mbappe and loanee Mauro Icardi are available again after recent injuries.
The PSG boss is all too aware that if Mbappe and Neymar can combine consistently, the reigning Ligue 1 champions will take some stopping.
"The relationship between the two is the key for us, they can bring us a lot of possibilities," Tuchel said.
"Mbappe has been hurt for weeks, we have to be patient, and tomorrow it's impossible for Kylian to play 90 minutes.
"We have to adapt to the situation and the opponent. Tomorrow, we will be able to play Mbappe and Icardi."