Both of these sides were involved in European competition this week, but an extra day's rest - and star names being given the night off could hand Tottenham the advantage this afternoon.
Dele Alli, Harry Kane and Jan Vertonghen were three of the names rested by Jose Mourinho against Bayern Munich, while Heung-min Son was only introduced as a late substitute.
Lineups
Predicted Wolves XI (3-4-3): Rui Patricio; Dendoncker, Coady, Saiss; Doherty, Ruben Neves, Moutinho, Jonny; Traore, Raul Jiminez, Diogo Jota.
Predicted Tottenham XI (4-2-3-1): Gazzaniga; Aurier, Alderweireld, Sanchez, Vertonghen; Sissoko, Dier; Lucas, Alli, Son; Kane.
Team news
Wolves injuries: Phil Ofosu-Ayeh (foot)
Wolves suspensions: None
Tottenham injuries: Hugo Lloris (dislocated elbow, out), Michel Vorm (calf, doubt), Erik Lamela (thigh, doubt), Harry Winks (ankle, doubt), Tanguy Ndombele (groin, doubt), Ben Davies (ankle, out).
Tottenham suspensions: None
Prediction: Wolves 1-2 Tottenham
Mourinho rested key players for their midweek Champions League clash with Bayern Munich, and that rest should prove the difference on Sunday with Wolves having been in Europa League action on Thursday night. A very tight game, which could go either way.