Chelsea make the short trip to the Brentford Community Stadium on Wednesday evening to face their west London rivals in the quarter finals of the Carabao Cup.
Thomas Tuchel's squad has been depleted due to an outbreak of coronavirus and the Blues will be hoping to avoid an upset against their less illustrious neighbours.
These two sides met in the Premier League back in October when Chelsea went back to Stamford Bridge with a narrow 1-0 victory.
Another success for the Blues is priced at 7/10 (1.70) with bet365 while Brentford can be backed at 17/4 (5.25) and the draw is offered at 13/5 (3.60).
With Romelu Lukaku and Timo Werner both missing, Mason Mount leads the betting to open the scoring with the England international offered at 9/2 (5.50).
For Brentford, with top scorer Ivan Toney out, Yone Wissa could lead the line and the Congolese forward can be backed at 9/1 (10.00) to break the deadlock.
The striker has already netted three goals in the competition.
Elsewhere in the market Hakim Ziyech is offered at 13/2 (7.50) while Jorginho can be backed at 8/1 (9.00).
Chelsea head into the game following a serious dip in form which has seen them win just one of their last five competitive fixtures.
The club did not want their game against Wolves at the weekend to go ahead given the positive coronavirus cases in the squad, yet the Premier League denied their request to have the match postponed and the Blues duly drew 0-0, losing more ground on the leaders.
While Wednesday night's game is a chance to reach a semi-final, it is also a chance to rest players in a packed schedule which has been further complicated by the ongoing pandemic.
Brentford are likely to see this game as a chance to claim a major scalp and reach the last four of a domestic competition and the hosts should be expected to view this clash in a much more positive light than their opponents.
The price of 96/100 (1.96) for Brentford to win with a +0.75 Asian handicap looks appealing.
This bet pays out in full if the hosts avoid defeat, while half of the initial stake is refunded if they lose by a single goal margin.
Odds correct at the time of writing. Please gamble responsibly.