Wan-Bissaka scored a ludicrous added-time own goal to gift France Under-21s an unlikely victory after England threw away their lead.
Phil Foden scored a stunner and France missed two penalties in an hectic encounter, before a Jonathan Ikone leveller (89) and Aaron Wan-Bissaka's horror own goal (90+5) gave France victory.
England had the better of the early chances but France missed the best chance to take the lead through the penalty spot as Moussa Dembele saw his effort saved by Dean Henderson (25) after Jay Clarke-Salter had been penalised for a handball.
England got a deserved opener after the break as Phil Foden slalomed through four France tackles before coolly finishing (54), but there was more madness at the other end as a VAR review saw Hamza Choudhury dismissed for a nasty tackle in the area, only for Houssem Aouar's penalty to hit the post (66).