On June 21, Beijing time (CEST), in the second group stage match of the FIFA World Cup, Sweden suffered a heavy 1-5 defeat to the Netherlands. Isak, who contributed 2 goals and 1 assist in the first group stage match, assisted Elanga in the 59th minute to reduce the deficit.
According to Stats Foot after the match, Isak, who scored 2 goals and provided 2 assists across the first two group stage matches, became the first Swedish player to be directly involved in 4 goals in a single FIFA World Cup since records began in 2000.