Liverpool and Arsenal will meet for the second time this season when they clash in the Carabao Cup.
The Reds ran out 3-1 winners at Anfield in the Premier League in August.
Jurgen Klopp's side were drawn against the Gunners following a routine 2-0 win at MK Dons in the Carabao Cup third round.
Arsenal, meanwhile, thrashed Nottingham Forest 5-0 at the Emirates in their third-round tie.
Liverpool and Arsenal last met in the League Cup back in 2009.
That game was also a fourth-round tie and the Gunners progressed with a 2-1 victory thanks to Nicklas Bendtner’s winner.
Team News
Liverpool
Klopp is set to ring the changes for Wednesday's Carabao Cup clash with Premier League rivals Arsenal.
Virgil Van Dijk suffered a dead leg in Sunday's 2-1 win over Tottenham and will be held back here with news Joel Matip could be sidelined for six weeks with a knee injury.
17-year-old summer signing Sepp van den Berg has been tipped to start at the heart of Liverpool's defence alongside Joe Gomez as a result.
Trent Alexander-Arnold will also be given the evening off, with 18-year-old right-back Neco Williams tipped to start at right-back. Ki-Jana Hoever would have been in with a shout to start but he is away on international duty with the Netherlands.
Other youngsters like Curtis Jones, Harvey Elliott and Rhian Brewster are also set to feature, while fringe players like Naby Keita, Alex Oxlade-Chamberlain and Adam Lallana will get starts against Arsenal.
Arsenal
Granit Xhaka may not be called upon on Wednesday night after his reaction to being subbed off against Crystal Palace at the weekend.
Look for Hector Bellerin to start at Anfield but Kieran Tierney may drop to the bench, as Unai Emery carefully manages their returns to full fitness.
Rob Holding will hope to get a run out at centre-back against Liverpool and will likely be paired with one of David Luiz or Sokratis.
Gabriel Martinelli started Arsenal's last Carabao Cup game but now Alexandre Lacazette is at full fitness his presence in the starting XI is not guarenteed.
Probable Lineups
Liverpool: Kelleher, Milner, Van den Berg, Gomez, Williams, Keita, Lallana, Ox, Origi, Brewster, Jones
Arsenal: Martinez, Bellerin, Holding, Luiz, Kolasinac, Torreira, Guendouzi, Pepe, Willock, Martinelli, Lacazette
Prediction
Liverpool 2-1 Arsenal