Manchester United will face Barcelona in the first knockout round of the Europa League in a tie featuring eight Champions League titles between the two teams.
The draw for the next stage of the competition took place in Switzerland on Monday lunchtime, with several big hitters in the draw either via qualification or through dropping out of the Champions League.
United against Barcelona was the major tie of the draw, but Juventus and Ajax were among the other teams to find out their fate ahead of the play-off round.
Juventus will play French side Nantes, with Ajax set to take on Union Berlin of Germany.
Jose Mourinho's Roma, who won the Conference League last season, will take on Salzburg, with six-time champions Sevilla set to face PSV.
Draw results:
Barcelona vs Man Utd
Juventus v Nantes
Sporting CP vs Midtjylland
Shakhtar Donetsk vs Rennes
Ajax vs Union Berlin
Leverkusen vs Monaco
Sevilla vs PSV
Salzburg vs Roma
The first legs will take place on Thursday, February 16, with the reverse fixtures taking place the following week.