Up to six Barcelona players could debut in a Bernabeu Clasico this weekend.
Frenkie de Jong, Antoine Griezmann, Ansu Fati, Junior Firpo, Neto and Martin Braithwaite are the players - and coach Quique Setien is doing the same.
The only player who has never played a game at the stadium for any side is Ansu Fati, who played eight minutes against Madrid in the 0-0 home game.
This is Antoine Griezmann's 16th game there, after 11 with Atletico and four with Real Sociedad, scoring four goals.
De Jong has the best memory, triumphing 4-1 there with Ajax last season in a historic humiliation of Los Blancos in the Champions League last 16.
Neto, Firpo and Braithwaite have all played there with Valencia, Betis and Leganes respectively. A 2-0 win for the full-back, a draw and a defeat for the keeper and two defeats for the Dane.
Sertien has played there nine times. He has three wins, two against Zidane with Las Palmas and Betis.