After sending his spot-kick crashing off the crossbar, the Barcelona star joked his other half's absence was the reason he did not score.
France won their Euro 2020 qualifier 4-1 as Kingsley Coman grabbed a double alongside goals from Olivier Giroud and Jonathan Ikone.
However, Griezmann was unable to add to the tally when presented with a first-half chance from the spot, his effort crashing off the crossbar and coming back into play.
Asked about his penalty miss, the Barcelona attacker said: "I don't know [what happened]. I don't know.
"As I said earlier, maybe it's because my wife didn't watch the game!
"I was on a good dynamic but we can't score every time. Too bad, I'll have to work on it."