Sassuolo look to Khouma Babacar after Kevin-Prince Boateng’s move to Barcelona, while Leonardo Pavoletti leads the way for Cagliari.
You’ll be able to follow all the action as it happens in today’s three Serie A games in the LIVEBLOG.
The Neroverdi are still reeling after the surprise switch that took Boateng to Barcelona this week, leaving them somewhat short-staffed in attack.
Babacar has been chosen to fill in, with support from Domenico Berardi and Filip Djuricic.
Stefano Sensi is injured, with Marlon injured, so Mehdi Bourabia steps in to the midfield.
Cagliari have been stuttering lately and miss Ragnar Klavan, Alberto Cerri, Marco Andreolli, Marco Sau and Lucas Castro.
Pavoletti is the focal point in attack, with Joao Pedro, Artur Ionita and Nicolò Barella feeding him.
Sassuolo: Consigli; Lirola, Magnani, Peluso, Rogerio; Locatelli, Magnanelli, Bourabia; Berardi, Babacar, Djuricic
Cagliari: Cragno; Srna, Ceppitelli, Pisacane, Lykogiannos; Faragò, Cigarini, Ionita, Barella; Joao Pedro, Pavoletti