Manchester United will welcome Brighton and Hove Albion to Old Trafford in Erik ten Hag's first Premier League match at the club on August 7.
Ten Hag then takes his new side to Brentford on the second weekend before a crunch early clash with Liverpool at Old Trafford on August 20.
United face consecutive away trips to Southampton and Leicester prior to the end of the match before hosting Arsenal in the first week of September.
Ten Hag also has a tricky end to the season with Leeds away and Liverpool at home in the Red Devils' final six games of the campaign.
Read the full list below:
All fixtures are subject to change once live TV schedule has been finalised.