Antonella Roccuzzo has celebrated her 31st anniversary with the closest ones. October 26 is a special day for Leo Messi's wife, since she is one year older.
The '10' Blaugrana has also spoken about his congratulations. Messi has posted a photograph in which all appear in family and with the text "Happy birthday my life!!! We love you." They have also congratulated the wives of the Barcelona players.
Barcelona go into the second leg against Real at The Bernabeu with the tie level at 1-1.
There will be another edition of El Clasico on Saturday when the sides do battle in La Liga.
Messi has scored 26 goals in 37 appearances against Real and will be determined to add to that tally during the upcoming two fixtures.
In the first leg at the Nou Camp Lucas Vazquez put Real ahead in the sixth minute but Barcelona equalised through Malcom in the 57th minute.
Messi came on as a substitute in that game but is in line to start on Wednesday and will be full of confidence following his superb hat-trick in the 4-2 victory over Sevilla last weekend.
So far this season Messi has scored 33 goals in 32 games, while he has provided 18 assists.
To reach this stage of the Copa del Rey, Barcelona have overcome Cultural Leonesa, Levante and Sevilla.