The Brazilian club announced the signing via their social media channels. Verona has secured 50% of the player's financial rights for a possible future sale.
His medical is scheduled for Thursday, January 8.
Mineiro announced: "Atletico Mineiro announces that it has completed the transfer of striker Isaac to Hellas Verona, of the Italian Serie A.
The deal includes the sale of part of the player's economic rights and the option to purchase an additional percentage. Having formed at the Mineiro base, Isaac will have the opportunity to gain experience and visibility in European football.
"Mineiro has retained 50% of the player's economic rights, allowing for a future financial return."